In recent years spirituality has emerged as a central focus in the field of health sciences. Astrong body of studies bring out the potential of spirituality/religiosity to promote and maintain physical and mental health and ameliorate the deleterious effects of psychosocial stress on health. Rresearchers and clinicians now believe in the important connection of spirituality with health and wellness of an individual's life. Researches in the area of behavioral medicine have also shown that the spirituality generates insightful effects on the bodily conditions. Studies indicate that enhancement of one's spirituality affect medical and health condition in terms of positive outcomes of patients' health care. The present reviewdeals the theoretical as well as empirical findings that include the influence of spirituality on health and well-being and its significance for patients suffering from various health problems. The findings indicate that spiritual need in medical care may create great encouraging results on a patient's health and well-being.